Human MAST205 (MAST2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAST2
Locus ID	23139
Kit Components	GA108067G1, MAST205 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108067G2, MAST205 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108067G3, MAST205 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319245, NM_001324320, NM_001324321, NM_015112
Synonyms	MAST205; MTSSK
Summary	Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB/Swiss-Prot Function]

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