Human TNRC6B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNRC6B
Locus ID	23112
Kit Components	GA108046G1, TNRC6B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108046G2, TNRC6B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108046G3, TNRC6B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001024843, NM_001162501, NM_015088
Synonyms	KIAA1093
Summary	Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.[UniProtKB/Swiss-Prot Function]

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