Human ERC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERC1
Locus ID	23085
Kit Components	GA108025G1, ERC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108025G2, ERC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108025G3, ERC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001301248, NM_015064, NM_032684, NM_178037, NM_178038, NM_178039, NM_178040, NR_027946, NR_027948, NR_027949
Synonyms	Cast2; ELKS; ERC-1; RAB6IP2
Summary	The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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