Human Senataxin (SETX) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SETX
Locus ID	23064
Kit Components	GA108010G1, Senataxin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108010G2, Senataxin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108010G3, Senataxin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015046, NM_001351527, NM_001351528
Synonyms	ALS4; AOA2; bA479K20.2; SCAR1
Summary	This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008]

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