Human WDFY3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WDFY3
Locus ID	23001
Kit Components	GA107961G1, WDFY3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107961G2, WDFY3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107961G3, WDFY3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014991, NM_178583, NM_178585
Synonyms	ALFY; ZFYVE25
Summary	This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]

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