Human EFR3B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EFR3B
Locus ID	22979
Kit Components	GA107942G1, EFR3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107942G2, EFR3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107942G3, EFR3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319099, NM_014971
Synonyms	KIAA0953
Summary	Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3B probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825).[UniProtKB/Swiss-Prot Function]

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