Human MSRB2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MSRB2
Locus ID	22921
Kit Components	GA107914G1, MSRB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107914G2, MSRB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107914G3, MSRB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012228
Synonyms	CBS-1; CBS1; CGI-131; MSRB; PILB
Summary	Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.[UniProtKB/Swiss-Prot Function]

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