Human KLF8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLF8
Locus ID	11279
Kit Components	GA107774G1, KLF8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107774G2, KLF8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107774G3, KLF8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159296, NM_001324099, NM_001324100, NM_001324102, NM_001324104, NM_001324105, NM_007250, NR_136704, NR_136705
Synonyms	BKLF3; ZNF741
Summary	This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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