Human GPR44 (PTGDR2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PTGDR2
Locus ID	11251
Kit Components	GA107752G1, GPR44 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107752G2, GPR44 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107752G3, GPR44 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004778
Synonyms	CD294; CRTH2; DL1R; DP2; GPR44
Summary	This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]

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