Human POLG2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POLG2
Locus ID	11232
Kit Components	GA107738G1, POLG2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107738G2, POLG2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107738G3, POLG2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007215
Synonyms	HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB
Summary	This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]

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