Human ZWINT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZWINT
Locus ID	11130
Kit Components	GA107655G1, ZWINT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107655G2, ZWINT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107655G3, ZWINT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001005413, NM_001005414, NM_007057, NM_032997
Synonyms	HZwint-1; KNTC2AP; SIP30; ZWINT1
Summary	This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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