Human ADAMTS13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADAMTS13
Locus ID	11093
Kit Components	GA107626G1, ADAMTS13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107626G2, ADAMTS13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107626G3, ADAMTS13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017587, NM_139025, NM_139026, NM_139027, NM_139028, NR_024514
Synonyms	ADAM-TS13; ADAMTS-13; C9orf8; vWF-CP; VWFCP
Summary	This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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