Human TMP21 (TMED10) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMED10
Locus ID	10972
Kit Components	GA107532G1, TMP21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107532G2, TMP21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107532G3, TMP21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006827
Synonyms	p23; P24(DELTA); p24d1; S31I125; S31III125; Tmp-21-I; TMP21
Summary	This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]

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