Human MSL3L1 (MSL3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MSL3
Locus ID	10943
Kit Components	GA107506G1, MSL3L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107506G2, MSL3L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107506G3, MSL3L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193270, NM_001282174, NM_006800, NM_078628, NM_078629, NM_078630
Synonyms	MSL3L1
Summary	This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]

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