Human MAGED2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAGED2
Locus ID	10916
Kit Components	GA107485G1, MAGED2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107485G2, MAGED2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107485G3, MAGED2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006787, NM_014599, NM_177433, NM_201222
Synonyms	11B6; BCG-1; BCG1; HCA10; MAGE-D2
Summary	This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

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