Human DHRS4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DHRS4
Locus ID	10901
Kit Components	GA107471G1, DHRS4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107471G2, DHRS4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107471G3, DHRS4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282987, NM_001282988, NM_001282989, NM_001282990, NM_001282991, NM_021004
Synonyms	CR; NRDR; PHCR; PSCD; SCAD-SRL; SDR-SRL; SDR25C1; SDR25C2
Summary	Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).[UniProtKB/Swiss-Prot Function]

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