Human ME3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ME3
Locus ID	10873
Kit Components	GA107446G1, ME3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107446G2, ME3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107446G3, ME3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001014811, NM_001161586, NM_006680, NM_001351934, NR_147828, NR_147829, NR_147830, NR_147831
Synonyms	NADP-ME
Summary	Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

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