Human Hsp105 (HSPH1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSPH1
Locus ID	10808
Kit Components	GA107408G1, Hsp105 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107408G2, Hsp105 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107408G3, Hsp105 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286503, NM_001286504, NM_001286505, NM_006644, NM_001349704
Synonyms	HSP105; HSP105A; HSP105B; NY-CO-25
Summary	This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]

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