Human USP39 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP39
Locus ID	10713
Kit Components	GA107338G1, USP39 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107338G2, USP39 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107338G3, USP39 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256725, NM_001256726, NM_001256727, NM_001256728, NM_006590, NR_046347
Synonyms	65K; CGI-21; HSPC332; SAD1; SNRNP65
Summary	Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome (PubMed:11350945, PubMed:26912367). Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity (PubMed:18728397).[UniProtKB/Swiss-Prot Function]

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