Human KLF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLF1
Locus ID	10661
Kit Components	GA107309G1, KLF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107309G2, KLF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107309G3, KLF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006563
Synonyms	CDAN4; EKLF; HBFQTL6; INLU
Summary	This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]

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