Human PRPF8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRPF8
Locus ID	10594
Kit Components	GA107250G1, PRPF8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107250G2, PRPF8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107250G3, PRPF8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006445
Synonyms	HPRP8; PRP8; PRPC8; RP13; SNRNP220
Summary	Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]

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