Human TXNL2 (GLRX3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GLRX3
Locus ID	10539
Kit Components	GA107203G1, TXNL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107203G2, TXNL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107203G3, TXNL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199868, NM_001321980, NM_006541
Synonyms	GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3
Summary	This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

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