Human Nebulette (NEBL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEBL
Locus ID	10529
Kit Components	GA107195G1, Nebulette gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107195G2, Nebulette gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107195G3, Nebulette gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001173484, NM_006393, NM_016365, NM_213569
Synonyms	LASP2; LNEBL
Summary	This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

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