Human TMEM147 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM147
Locus ID	10430
Kit Components	GA107112G1, TMEM147 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107112G2, TMEM147 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107112G3, TMEM147 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242597, NM_001242598, NM_006326, NM_032635
Synonyms	NIFIE14
Summary	Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (PubMed:21056967). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (PubMed:21056967).[UniProtKB/Swiss-Prot Function]

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