Human CD2BP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CD2BP2
Locus ID	10421
Kit Components	GA107104G1, CD2BP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107104G2, CD2BP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107104G3, CD2BP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001243646, NM_006110, NR_024465
Synonyms	FWP010; LIN1; PPP1R59; Snu40; U5-52K
Summary	This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]

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