Human HEC1 (NDC80) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NDC80
Locus ID	10403
Kit Components	GA107091G1, HEC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107091G2, HEC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107091G3, HEC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006101
Synonyms	HEC; HEC1; HsHec1; hsNDC80; KNTC2; TID3
Summary	This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

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