Human BPNT1 activation kit by CRISPRa
CAT#: GA107070
BPNT1 CRISPRa kit - CRISPR gene activation of human 3'(2'), 5'-bisphosphate nucleotidase 1
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | BPNT1 |
Locus ID | 10380 |
Kit Components | GA107070G1, BPNT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107070G2, BPNT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107070G3, BPNT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001286149, NM_001286150, NM_001286151, NM_006085 |
Synonyms | HEL20; PIP |
Summary | BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN416622 | BPNT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |