Human HMG20A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HMG20A
Locus ID	10363
Kit Components	GA107061G1, HMG20A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107061G2, HMG20A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107061G3, HMG20A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001304504, NM_001304505, NM_018200
Synonyms	HMGX1; HMGXB1
Summary	Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).[UniProtKB/Swiss-Prot Function]

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