Human RRAGB activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RRAGB
Locus ID	10325
Kit Components	GA107037G1, RRAGB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107037G2, RRAGB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107037G3, RRAGB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006064, NM_016656, NM_001354011, NM_001354013, NR_148683, NR_148684, NR_148685, NR_148686, NR_148687, NR_148688, NR_148689, NR_148690, NR_148691, NR_148692
Synonyms	bA465E19.1; RAGB
Summary	Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

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