Human PATJ activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PATJ
Locus ID	10207
Kit Components	GA106937G1, PATJ gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106937G2, PATJ gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106937G3, PATJ gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005799, NM_170605, NM_176877, NM_176878, NM_001350145
Synonyms	Cipp, PATJ
Summary	This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]

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