Human RBM7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RBM7
Locus ID	10179
Kit Components	GA106915G1, RBM7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106915G2, RBM7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106915G3, RBM7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286045, NM_001286046, NM_001286047, NM_001286048, NM_016090
Summary	Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). Possible involved in germ cell RNA processing and meiosis (Probable).[UniProtKB/Swiss-Prot Function]

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