Human PLXNC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLXNC1
Locus ID	10154
Kit Components	GA106894G1, PLXNC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106894G2, PLXNC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106894G3, PLXNC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005761, NR_037687
Synonyms	CD232; PLXN-C1; VESPR
Summary	This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]

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