Human SNURPORTIN1 (SNUPN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNUPN
Locus ID	10073
Kit Components	GA106827G1, SNURPORTIN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106827G2, SNURPORTIN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106827G3, SNURPORTIN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042581, NM_001042588, NM_005701
Synonyms	KPNBL; RNUT1; Snurportin1
Summary	The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

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