Human HDAC6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HDAC6
Locus ID	10013
Kit Components	GA106781G1, HDAC6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106781G2, HDAC6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106781G3, HDAC6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001321225, NM_001321226, NM_001321227, NM_001321228, NM_001321229, NM_001321230, NM_001321231, NM_006044, NR_135591, NR_135592, NR_135593
Synonyms	CPBHM; HD6; JM21; PPP1R90
Summary	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]

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