Human DGCR2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DGCR2
Locus ID	9993
Kit Components	GA106766G1, DGCR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106766G2, DGCR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106766G3, DGCR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001173533, NM_001173534, NM_001184781, NM_005137, NR_033674
Synonyms	DGS-C; IDD; LAN; SEZ-12
Summary	Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

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