Human USP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP3
Locus ID	9960
Kit Components	GA106739G1, USP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106739G2, USP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106739G3, USP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256702, NM_006537, NR_046341, NR_046342
Synonyms	SIH003; UBP
Summary	Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.[UniProtKB/Swiss-Prot Function]

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