Human USP15 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP15
Locus ID	9958
Kit Components	GA106738G1, USP15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106738G2, USP15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106738G3, USP15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252078, NM_001252079, NM_006313, NM_001351159, NM_001351160, NM_001351161, NM_001351162, NM_001351163, NM_001351164, NM_001351165, NM_001351166, NR_147078, NR_147079, NR_147080, NR_147081, NR_147082
Synonyms	UNPH-2; UNPH4
Summary	This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]

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