Human MRC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MRC2
Locus ID	9902
Kit Components	GA106688G1, MRC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106688G2, MRC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106688G3, MRC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006039
Synonyms	CD280; CLEC13E; ENDO180; UPARAP
Summary	This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]

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