Human OSBPL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OSBPL2
Locus ID	9885
Kit Components	GA106673G1, OSBPL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106673G2, OSBPL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106673G3, OSBPL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278649, NM_014835, NM_144498, NM_001363878
Synonyms	DFNA67; DNFA67; ORP-2; ORP2
Summary	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]

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