Human BTF (BCLAF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BCLAF1
Locus ID	9774
Kit Components	GA106577G1, BTF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106577G2, BTF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106577G3, BTF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077440, NM_001077441, NM_001301038, NM_014739, NM_001363659
Synonyms	bK211L9.1; BTF
Summary	This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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