Human GARRE1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GARRE1
Locus ID	9710
Kit Components	GA106520G1, GARRE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106520G2, GARRE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106520G3, GARRE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014686
Summary	Acts as an effector of RAC1 (PubMed:31871319). Associates with CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation (PubMed:29395067). May also play a role in miRNA silencing machinery (PubMed:29395067).[UniProtKB/Swiss-Prot Function]

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