Human SAPS2 (PPP6R2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP6R2
Locus ID	9701
Kit Components	GA106512G1, SAPS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106512G2, SAPS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106512G3, SAPS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242898, NM_001242899, NM_001242900, NM_014678, NM_001351641, NM_001351642, NM_001351643, NM_001351644, NM_001351645, NM_001351646, NM_001351647, NM_001351648, NM_001365836
Synonyms	KIAA0685; PP6R2; SAP190; SAPS2
Summary	The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. [provided by RefSeq, May 2017]

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