Human ARHGEF10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF10
Locus ID	9639
Kit Components	GA106457G1, ARHGEF10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106457G2, ARHGEF10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106457G3, ARHGEF10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308152, NM_001308153, NM_014629
Synonyms	GEF10; SNCV
Summary	This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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