Human Serine Palmitoyltransferase (SPTLC2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPTLC2
Locus ID	9517
Kit Components	GA106363G1, Serine Palmitoyltransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106363G2, Serine Palmitoyltransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106363G3, Serine Palmitoyltransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004863
Synonyms	hLCB2a; HSN1C; LCB2; LCB2A; NSAN1C; SPT2
Summary	This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]

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