Human STOML1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STOML1
Locus ID	9399
Kit Components	GA106271G1, STOML1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106271G2, STOML1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106271G3, STOML1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256672, NM_001256673, NM_001256674, NM_001256675, NM_001256676, NM_001256677, NM_001324226, NM_001324227, NM_001324228, NM_001324229, NM_001324230, NM_004809
Synonyms	hUNC-24; SLP-1; STORP
Summary	May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed:23082202).[UniProtKB/Swiss-Prot Function]

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