Human CCPG1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CCPG1
Locus ID	9236
Kit Components	GA106159G1, CCPG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106159G2, CCPG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106159G3, CCPG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204450, NM_001204451, NM_004748, NM_020739
Synonyms	CPR8
Summary	Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.[UniProtKB/Swiss-Prot Function]

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