Human DEDD activation kit by CRISPRa

CAT#: GA106128

DEDD CRISPRa kit - CRISPR gene activation of human death effector domain containing



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DEDD
Locus ID 9191
Kit Components

GA106128G1, DEDD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106128G2, DEDD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106128G3, DEDD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001039711, NM_001039712, NM_001330765, NM_004216, NM_032998
Synonyms CASP8IP1; DEDD1; DEFT; FLDED1; KE05
Summary This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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