Human SLC28A1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC28A1
Locus ID	9154
Kit Components	GA106104G1, SLC28A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106104G2, SLC28A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106104G3, SLC28A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001287761, NM_001287762, NM_001321721, NM_001321722, NM_004213, NM_201651
Synonyms	CNT1; HCNT1
Summary	Sodium-dependent and pyrimidine-selective. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). It also transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.[UniProtKB/Swiss-Prot Function]

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