Human FCP1 (CTDP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTDP1
Locus ID	9150
Kit Components	GA106101G1, FCP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106101G2, FCP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106101G3, FCP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001202504, NM_001318511, NM_004715, NM_048368
Synonyms	CCFDN; FCP1
Summary	This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

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