Human SLC16A3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC16A3
Locus ID	9123
Kit Components	GA106076G1, SLC16A3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106076G2, SLC16A3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106076G3, SLC16A3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042422, NM_001042423, NM_001206950, NM_001206951, NM_001206952, NM_004207
Synonyms	MCT-3; MCT-4; MCT 3; MCT3; MCT 4; MCT4
Summary	Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]

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